Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210418 | 0.87 | ALDH1A1 (0.79) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL9204774 | 0.85 | KMT2A (0.66) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL29677221 | 0.85 | KMT2A (0.66) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL17164233 | 0.84 | ALDH1A1 (0.63) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL28650627 | 0.84 | ALDH1A1 (0.63) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL6589340 | 0.84 | MAOB (0.68) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL26195616 | 0.84 | MAOB (0.68) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL29270309 | 0.84 | MAOA (0.65) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL6591353 | 0.83 | MAOB (0.70) | ALDH1A1KMT2AHPGDHSD17B10TP53 | |
| SCHEMBL10063475 | 0.82 | MAOB (0.74) | ALDH1A1KMT2AHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |