Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425818 | 0.82 | ALDH1A1 (0.47) | KDM4EL3MBTL1GLAPOLBALDH1A1 | |
| SCHEMBL623383 | 0.75 | MAPT (0.52) | KDM4EL3MBTL1ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL9426239 | 0.74 | ADORA1 (0.46) | KDM4EL3MBTL1GLANPC1POLB | |
| SCHEMBL9437225 | 0.74 | HDAC6 (0.50) | KDM4EL3MBTL1NPC1POLBRAB9A | |
| SCHEMBL11184731 | 0.69 | ALDH1A1 (0.45) | KDM4EGLANPC1POLBRAB9A | |
| SCHEMBL622747 | 0.68 | ADORA1 (0.52) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL223748 | 0.67 | MAPT (0.55) | KDM4EL3MBTL1GLANPC1POLB | |
| SCHEMBL9294591 | 0.67 | ALDH1A1 (0.39) | KDM4EL3MBTL1GLAPOLBALDH1A1 | |
| SCHEMBL11559664 | 0.66 | MAPT (0.46) | KDM4EL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL9437227 | 0.66 | DRD4 (0.46) | KDM4EGLAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000273097-A | PRODUCTION OF 4,5,6,7-TETRAHYDROTHIENO[3,2c]PYRIDINE-2- CARBOXYLIC ACID DERIVATIVE | FUJI PHOTO FILM CO LTD | 2000-10-03 | — | — | JP | disclosed |
| US-5364941-A | 5-acyl-4,5,6,7-tetrahydrothieno (3,2-C)pyridine-2-carboxylic acid derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| US-5296603-A | 3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0573954-A1 | 5-Acyl-4,5,6,7-tetrahydrothieno 3,2-c pyridine-2-carboxylic acid derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0573955-A1 | 3-Amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |