Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.45 |
| ▸ | FAP | Q12884 | 13/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.45 |
| ▸ | PREP | P48147 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941599 | 0.70 | — | — | |
| SCHEMBL8430009 | 0.70 | — | — | |
| SCHEMBL13751280 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL2038268 | 0.70 | — | — | |
| SCHEMBL13751142 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL12372017 | 0.68 | FAP (0.69) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL13263677 | 0.68 | FAP (0.69) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL7897923 | 0.67 | — | — | |
| SCHEMBL172898 | 0.67 | — | — | |
| SCHEMBL407643 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144379-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2009006473-A2 | PRO-SOFT POLYPEPTIDE PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2009-01-08 | — | — | WO | disclosed |