Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085716 | 0.95 | CALM1 (0.55) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL11087087 | 0.95 | LTA4H (0.53) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL1263547 | 0.95 | TAAR1 (0.60) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL30000562 | 0.95 | TAAR1 (0.60) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL29459538 | 0.95 | TAAR1 (0.60) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL2938820 | 0.93 | CALM1 (0.57) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL30674456 | 0.93 | CALM1 (0.57) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL25062024 | 0.89 | MAPT (0.57) | TAAR1LTA4HIDO1DAOSAE1 | |
| SCHEMBL8993375 | 0.89 | LTA4H (0.49) | TAAR1LTA4HIDO1ACHEDAO | |
| SCHEMBL20804858 | 0.89 | LTA4H (0.49) | TAAR1LTA4HIDO1ACHEDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |