Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094695 | 0.95 | TLR8 (0.48) | TLR8IDH1HTR2ATYRALOX5 | |
| SCHEMBL8096168 | 0.93 | TLR8 (0.47) | TLR8HTR2ATYRALOX5CNR1 | |
| SCHEMBL8098813 | 0.93 | TLR8 (0.47) | TLR8HTR2ATYRALOX5CNR1 | |
| SCHEMBL8101651 | 0.93 | TLR8 (0.47) | TLR8HTR2ATYRALOX5CNR1 | |
| SCHEMBL8095605 | 0.91 | CNR1 (0.42) | TLR8CNR1CNR2LTA4HMTNR1A | |
| SCHEMBL8102088 | 0.91 | TLR8 (0.42) | TLR8HTR2ALMNACNR1CNR2 | |
| SCHEMBL8095678 | 0.89 | CALM1 (0.44) | IDH1HTR2ACALM1LMNABCL2 | |
| SCHEMBL8093734 | 0.87 | HTR2A (0.55) | TLR8HTR2ACALM1LMNABCL2 | |
| SCHEMBL8771450 | 0.87 | TLR8 (0.48) | TLR8HTR2A | |
| SCHEMBL8771502 | 0.87 | TLR8 (0.48) | TLR8HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |