Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096168 | 1.00 | TLR8 (0.47) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8101651 | 1.00 | TLR8 (0.47) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8094695 | 0.98 | TLR8 (0.48) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8093845 | 0.93 | TLR8 (0.43) | TLR8CNR1CNR2ALOX5TYR | |
| SCHEMBL8771450 | 0.93 | TLR8 (0.48) | TLR8CYP3A4MAPTHTR2A | |
| SCHEMBL8771502 | 0.93 | TLR8 (0.48) | TLR8CYP3A4MAPTHTR2A | |
| SCHEMBL8099834 | 0.92 | CNR1 (0.46) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8099736 | 0.92 | CNR1 (0.46) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8086350 | 0.92 | CNR1 (0.46) | TLR8KCNH2LIPGGPR3CNR1 | |
| SCHEMBL8094286 | 0.91 | TLR8 (0.46) | TLR8KCNH2LIPGGPR3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |