Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093868 | 0.89 | FFAR4 (0.35) | PPARG | |
| SCHEMBL7462597 | 0.88 | PPARD (0.36) | TDP1PDK2PPARDPPARAKDM4E | |
| SCHEMBL7458315 | 0.88 | PPARD (0.34) | TDP1PPARDKDM4E | |
| SCHEMBL7452381 | 0.82 | PPARD (0.36) | TDP1PDK2PPARDPPARAKDM4E | |
| SCHEMBL7461699 | 0.81 | POLB (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL8096320 | 0.79 | PPARG (0.37) | TDP1PDK2KDM4EALDH1A1HPGD | |
| SCHEMBL7460264 | 0.79 | — | — | |
| SCHEMBL7458306 | 0.79 | FFAR4 (0.34) | PPARDPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL7457256 | 0.77 | PPARD (0.33) | PPARDPPARAPPARG | |
| SCHEMBL6770359 | 0.77 | BCAT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156700-A | 3-(1,2-Benzisothiazol- and isoxazol-5-yl)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3H)-pyrimidinone or thione herbicidal agents | AMERICAN CYANMID COMPANY (US) | 2000-12-05 | — | — | US | disclosed |