Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093867 | 0.92 | PTGS2 (0.55) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8092465 | 0.91 | PTGS2 (0.46) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8095170 | 0.88 | PTGS2 (0.46) | PTGS2PTGS1CNR1KDM4EPOLB | |
| SCHEMBL8099377 | 0.87 | KDM4E (0.56) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8093664 | 0.86 | KDM4E (0.45) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8094767 | 0.85 | CNR1 (0.52) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8096123 | 0.85 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2KDM4E | |
| SCHEMBL8095836 | 0.85 | KDM4E (0.45) | CNR1CNR2KDM4EPOLBMEN1 | |
| SCHEMBL8100868 | 0.85 | CA2 (0.51) | PTGS2CNR1CNR2KDM4EPOLB | |
| SCHEMBL8094021 | 0.85 | KDM4E (0.47) | CNR1CNR2KDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | claimed |