Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 19/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836739 | 0.84 | CCR5 (1.00) | CCR5 | |
| SCHEMBL7835509 | 0.81 | CCR5 (0.87) | CCR5 | |
| SCHEMBL7817814 | 0.80 | CCR5 (0.85) | CCR5 | |
| SCHEMBL7826200 | 0.78 | CCR5 (0.78) | CCR5ALDH1A1 | |
| SCHEMBL7836855 | 0.78 | CCR5 (0.71) | CCR5 | |
| SCHEMBL7833942 | 0.74 | CCR5 (1.00) | CCR5 | |
| SCHEMBL7825773 | 0.74 | CCR5 (0.65) | CCR5MEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL7836524 | 0.70 | CCR5 (1.00) | CCR5MEN1TSHRKMT2A | |
| SCHEMBL5174991 | 0.70 | CCR5 (0.74) | CCR5MEN1KMT2A | |
| SCHEMBL8090790 | 0.69 | CCR5 (1.00) | CCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166037-A | Pyrrolidine and piperidine modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2000-12-26 | — | — | US | disclosed |