SCHEMBL8094399

SCHEMBL8094399

CC(c1[c]cccc1)c1ccc(C#N)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.38
TSHR P16473 1/20 0.38
OPRD1 P41143 1/20 0.36
CYP2A6 P11509 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP19A1 P11511 5/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HDAC8 Q9BY41 2/20 0.33
F2R P25116 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8939777 0.80 TYR (0.36) ALDH1A1
SCHEMBL8939712 0.80 TYR (0.36) ALDH1A1
SCHEMBL2468065 0.80 TYR (0.36) ALDH1A1
SCHEMBL4405618 0.77 ESR1 (0.54) TSHRALDH1A1
SCHEMBL17071852 0.76 TSHR (0.54) ALOX5APTSHROPRD1CYP2A6ALDH1A1
SCHEMBL10700367 0.76 TSHR (0.54) ALOX5APTSHROPRD1CYP2A6ALDH1A1
SCHEMBL17071848 0.76 TSHR (0.54) ALOX5APTSHROPRD1CYP2A6ALDH1A1
SCHEMBL7799578 0.75 CYP2A6 (0.52) TSHRCYP2A6ALDH1A1CYP19A1HDAC8
SCHEMBL4433093 0.75
SCHEMBL7901193 0.73 ALDH1A1 (0.44) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6160194-A Soil decontamination using ferric chelates and peroxide THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) 2000-12-12 US disclosed
US-5232484-A Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) 1993-08-03 US disclosed