SCHEMBL809468

SCHEMBL809468

O=C1CCCC[C@H]1[C@H](CC(F)F)C[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.36
CYP2D6 P10635 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809469 0.82 CYP2D6 (0.40) CA1CYP2D6NOS3NOS1NOS2
SCHEMBL809542 0.78 CYP2D6 (0.37) CA1CYP2D6NOS3NOS1NOS2
SCHEMBL6979377 0.74 NOS3 (0.38) CA1CYP2D6NOS3NOS1NOS2
SCHEMBL27165147 0.70 CA1 (0.43) CA1
SCHEMBL27165038 0.70 CA1 (0.43) CA1
SCHEMBL10491745 0.70 CA1 (0.43) CA1
SCHEMBL27165146 0.70 CA1 (0.43) CA1
SCHEMBL10491741 0.70 CA1 (0.43) CA1
SCHEMBL813507 0.69 CA1 (0.53) CA1
SCHEMBL809451 0.69 CA1 (0.53) CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968734-B2 Organocatalysts and methods of use in chemical synthesis STC.UNM (US) 2011-06-28 US disclosed
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis STC.UNM (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis SCO2, CBR1, CBR3 CA1 152/4885CYP2D6 193/4885NOS3 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.