SCHEMBL809469

SCHEMBL809469

CC[C@H](C[N+](=O)[O-])[C@@H]1CCCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
CA1 P00915 4/20 0.37
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
KMT2A Q03164 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
ALDH1A1 P00352 4/20 0.31
MAPT P10636 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809542 0.84 CYP2D6 (0.37) CYP2D6CA1CA2CA4KMT2A
SCHEMBL29107866 0.83 CYP2D6 (0.47) CYP2D6CA1CA2CA4KMT2A
SCHEMBL809468 0.82 CA1 (0.36) CYP2D6CA1CA2CA4NOS3
SCHEMBL23907959 0.77 CYP2D6 (0.43) CYP2D6CA1CA2CA4KMT2A
SCHEMBL6979377 0.76 NOS3 (0.38) CYP2D6CA1CA2CA4KMT2A
SCHEMBL486885 0.73 CYP2D6 (0.40) CYP2D6CA1CA2CA4KMT2A
SCHEMBL6969466 0.73 CYP2D6 (0.50) CYP2D6CA1KMT2AALDH1A1
SCHEMBL15577087 0.72 CYP2D6 (0.49) CYP2D6CA1CA2CA4KMT2A
SCHEMBL27204357 0.72 ALDH1A1 (0.43) CA1ALDH1A1MAPTPOLB
SCHEMBL27204359 0.72 ALDH1A1 (0.43) CA1ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968734-B2 Organocatalysts and methods of use in chemical synthesis STC.UNM (US) 2011-06-28 US disclosed
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis STC.UNM (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis SCO2, CBR1, CBR3 CYP2D6 193/4885CA1 152/4885CA2 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.