Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 9/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 9/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408565 | 0.97 | CES1 (0.55) | CES1CES2LPAR1LPAR3FDPS | |
| SCHEMBL12059209 | 0.92 | CES1 (0.48) | CES1CES2LPAR1LPAR3 | |
| SCHEMBL28792699 | 0.83 | CES1 (0.47) | CES1CES2LPAR1LPAR3FDPS | |
| SCHEMBL9408624 | 0.81 | CES1 (0.46) | CES1CES2LPAR1LPAR3FDPS | |
| SCHEMBL28851669 | 0.81 | CES1 (0.41) | CES1CES2LPAR1LPAR3FDPS | |
| SCHEMBL2345427 | 0.79 | CES2 (0.45) | CES1CES2LPAR1LPAR3FDPS | |
| SCHEMBL9179320 | 0.78 | — | — | |
| SCHEMBL7779410 | 0.78 | — | — | |
| SCHEMBL30164867 | 0.78 | FDPS (0.46) | CES2FDPSGGPS1 | |
| SCHEMBL15789008 | 0.77 | CES2 (0.43) | CES1CES2LPAR1LPAR3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022722-A | REGENERATION OF DENATURED POLYPEPTIDE; CONTACTING A DENATURED POLYPEPTIDE ADSORBED TO SOLID SUPPORT WITH TRIFLUOROETHANOL | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | claimed |
| EP-4116289-A1 | SYNTHESIS METHOD FOR FLUORINE-CONTAINING CHIRAL AMINE COMPOUND | Asymchem Laboratories (Tianjin) Co., Ltd. (CN) | 2023-01-11 | — | — | EP | disclosed |
| US-6022722-A | REGENERATION OF DENATURED POLYPEPTIDE; CONTACTING A DENATURED POLYPEPTIDE ADSORBED TO SOLID SUPPORT WITH TRIFLUOROETHANOL | HUELS AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| EP-0884323-A1 | Renaturation of proteins by fluorinated reagents | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-12-16 | — | — | EP | disclosed |