Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.88 |
| ▸ | CCR1 | P32246 | 3/20 | 0.88 |
| ▸ | CCR5 | P51681 | 3/20 | 0.88 |
| ▸ | CCR8 | P51685 | 3/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.88 |
| ▸ | METAP1 | P53582 | 1/20 | 0.88 |
| ▸ | BLM | P54132 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.88 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.88 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL29728717 | 0.97 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL230578 | 0.97 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30635227 | 0.97 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL35210403 | 0.97 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9644480 | 0.97 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1181563 | 0.94 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9299834 | 0.94 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL8685663 | 0.94 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7732129 | 0.94 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2250385 | 0.94 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120081782-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine | 天津均凯农业科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-114752020-A | Method for preparing polyether polycarboxylic acid type high-efficiency water reducing agent from high-boiling residues at bottom of polyethylbenzene tower | 中国石油化工股份有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-120081782-A | Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine | 天津均凯农业科技有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-114752020-B | Method for preparing polyether polycarboxylic acid type high-efficiency water reducer from polyethylbenzene tower bottom high-boiling-point substance | 中国石油化工股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114752020-B | Method for preparing polyether polycarboxylic acid type high-efficiency water reducer from polyethylbenzene tower bottom high-boiling-point substance | 中国石油化工股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114752020-A | Method for preparing polyether polycarboxylic acid type high-efficiency water reducing agent from high-boiling residues at bottom of polyethylbenzene tower | 中国石油化工股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114752020-A | Method for preparing polyether polycarboxylic acid type high-efficiency water reducing agent from high-boiling residues at bottom of polyethylbenzene tower | 中国石油化工股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113698546-B | Method for preparing polyether polycarboxylic acid type high-efficiency water reducing agent from high-boiling residues at bottom of polyethylbenzene tower | 中国石油化工股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-113698546-B | Method for preparing polyether polycarboxylic acid type high-efficiency water reducing agent from high-boiling residues at bottom of polyethylbenzene tower | 中国石油化工股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-109096149-B | Process for the preparation of beta-arylamines | 富兰克科技（深圳）股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-1845122-B1 | POLYARYLENE, PROCESS FOR PRODUCING THE SAME, SOLID POLYELECTROLYTE, AND PROTON-CONDUCTIVE FILM | JSR CORP (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-20050064260-A1 | Membrane-electrode structure for solid polymer fuel cell | JSR CORPORATION | 2005-03-24 | — | — | US | disclosed |
| EP-1517390-A2 | Membrane-electrode structure for solid polymer fuel cell | HONDA MOTOR CO., Ltd. (JP) | 2005-03-23 | — | — | EP | disclosed |
| US-20040214065-A1 | Polymer electrolyte and proton-conducting membrane | JSR CORPORATION (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1465277-A1 | Solid polymer electrolyte and protonconducting membrane | HONDA MOTOR CO., Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-20020172850-A1 | Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same | HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION | 2002-11-21 | — | — | US | disclosed |
| EP-0956312-B1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR CORP (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6300465-B1 | Process for producing phenylene-containing polymer and film-forming material | JSR CORPORATION (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0956312-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR Corporation (JP) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033836-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR CORPORATION (JP) | 1998-08-06 | — | — | WO | disclosed |