Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CCR1 | P32246 | 3/20 | 0.93 |
| ▸ | CCR5 | P51681 | 3/20 | 0.93 |
| ▸ | CCR8 | P51685 | 3/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | METAP1 | P53582 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.93 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.93 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL9644480 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL35210403 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29728717 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL30635227 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL809479 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2250385 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29643175 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3751791 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL196501 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29643006 | 0.97 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103790-A1 | NAPHTHYRIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏豪森药业集团有限公司 | 2026-05-21 | — | — | WO | claimed |
| JP-8176067-A | — | — | None | — | — | JP | disclosed |
| JP-8291099-A | — | — | None | — | — | JP | disclosed |
| WO-2026103790-A1 | NAPHTHYRIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏豪森药业集团有限公司 | 2026-05-21 | — | — | WO | disclosed |
| CN-122035860-A | Modified lignin-based porous carbon, preparation method thereof and silicon-carbon negative electrode material | 上海汉禾生物新材料科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-116332739-A | Preparation method and application of ring belt arene and derivative | 清华大学 | 2023-06-27 | — | — | CN | disclosed |
| EP-2519554-B1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | DU PONT (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-1906473-B1 | ELECTRODE PASTE FOR USE IN SOLID POLYMER FUEL CELL | JSR CORP (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-8609804-B2 | Polyarylene polymers and processes for preparing | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| US-8399148-B2 | Varnish for a solid polymer fuel cell | JSR CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-6300465-B1 | Process for producing phenylene-containing polymer and film-forming material | JSR CORPORATION (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0956312-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR Corporation (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5945501-A | Epoxy resin compositions including novel phenol novolak condensates produced from bis(methoxymethyl)biphenyls | UBE INDUSTRIES, LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| WO-1998033836-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR CORPORATION (JP) | 1998-08-06 | — | — | WO | disclosed |
| US-5612442-A | Phenol novolak condensate and bis(methoxymethyl)biphenyl for production thereof | UBE INDUSTRIES, LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| JP-H08291099-A | BIS(METHOXYMETHYL)BIPHENYL AND ITS PRODUCTION | UBE IND LTD | 1996-11-05 | — | — | JP | disclosed |
| JP-H08176067-A | PRODUCTION OF 4,4'-DIACETOXYBIPHENYL | UBE IND LTD | 1996-07-09 | — | — | JP | disclosed |
| US-5102971-A | Polyphenyl resin | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
| EP-0436111-A2 | Compositions of substituted homopoly-p-phenylenes and thermoplastics | BAYER AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| EP-0348717-A2 | Soluble polyaromatics | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |