Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.42 |
| ▸ | PI4KA | P42356 | 3/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.42 |
| ▸ | GMPS | P49915 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.39 |
| ▸ | AHCY | P23526 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745239 | 0.79 | PI4K2A (0.52) | ADORA2AADORA3PRMT5WDR77SLC28A1 | |
| SCHEMBL9813098 | 0.78 | AHCY (0.49) | ADORA2AADORA3PRMT5WDR77SLC28A1 | |
| SCHEMBL10427714 | 0.78 | ADORA2A (0.50) | ADORA2AADORA3PRMT5WDR77SLC28A1 | |
| SCHEMBL8094883 | 0.78 | ADORA2A (0.50) | ADORA2AADORA3PRMT5WDR77SLC28A1 | |
| SCHEMBL5180860 | 0.77 | ADORA2A (0.49) | ADORA2AADORA3PRMT5WDR77SLC28A1 | |
| SCHEMBL27889983 | 0.76 | SLC28A1 (0.48) | ADORA2AADORA3SLC28A1PI4K2API4KA | |
| SCHEMBL6536153 | 0.75 | PI4KA (0.46) | ADORA2AADORA3SLC28A1PI4K2API4KA | |
| SCHEMBL2053006 | 0.75 | ADORA2A (0.48) | ADORA2AADORA3SLC28A1PI4K2API4KA | |
| Calcium SCHEMBL5323177 | 0.74 | ADORA2A (0.47) | ADORA2AADORA3SLC28A1PI4K2API4KA | |
| SCHEMBL27730981 | 0.73 | SLC28A1 (0.51) | ADORA2AADORA3SLC28A1PI4K2API4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5065285-A | — | — | None | — | — | JP | disclosed |
| JP-H0565285-A | N-ACYLNUCLEOSIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ASAHI CHEM IND CO LTD | 1993-03-19 | — | — | JP | disclosed |