Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.52 |
| ▸ | PI4KA | P42356 | 3/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | GMPS | P49915 | 1/20 | 0.47 |
| ▸ | AHCY | P23526 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ADA | P00813 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22460509 | 0.88 | PI4K2A (0.52) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL10427714 | 0.85 | ADORA2A (0.50) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL8094883 | 0.85 | ADORA2A (0.50) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL5180860 | 0.84 | ADORA2A (0.49) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL439243 | 0.81 | SLC28A1 (0.56) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL29799646 | 0.81 | SLC28A1 (0.56) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL9446941 | 0.79 | ADORA2A (0.43) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL20833563 | 0.78 | ADORA2A (0.51) | PI4K2API4KAPI4K2BPI4KBADORA2A | |
| SCHEMBL28266848 | 0.77 | TK1 (0.44) | ADORA3 | |
| SCHEMBL28171063 | 0.76 | ADORA2A (0.51) | PI4K2API4KAPI4K2BPI4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118879-A2 | ANTIVIRAL COMPOSITIONS COMPRISING 2 COMPOUNDS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-02 | — | — | WO | disclosed |