Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083456 | 0.95 | MMP8 (0.46) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8083554 | 0.95 | MMP8 (0.46) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8083488 | 0.94 | MMP8 (0.45) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8095058 | 0.87 | SPHK1 (0.43) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8089921 | 0.85 | MMP8 (0.48) | MMP8EPHX2SPHK1F2EPHX1 | |
| SCHEMBL8083610 | 0.85 | MMP8 (0.54) | MMP8EPHX2SPHK1HPGDEPHX1 | |
| SCHEMBL8083449 | 0.83 | EPHX2 (0.41) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8083551 | 0.83 | EPHX2 (0.41) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8083486 | 0.82 | EPHX2 (0.41) | MMP8EPHX2SPHK1HPGDF2 | |
| SCHEMBL8095448 | 0.82 | MMP8 (0.38) | MMP8EPHX2SPHK1HPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |