Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083449 | 0.96 | EPHX2 (0.41) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8083551 | 0.96 | EPHX2 (0.41) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8083486 | 0.95 | EPHX2 (0.41) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8095062 | 0.87 | MMP8 (0.48) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8089916 | 0.86 | MMP8 (0.44) | SPHK1EPHX2MMP8F2 | |
| SCHEMBL8096623 | 0.85 | MC4R (0.39) | F2TPSAB1 | |
| SCHEMBL8083456 | 0.82 | MMP8 (0.46) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8083554 | 0.82 | MMP8 (0.46) | SPHK1EPHX2MMP8F2TPSAB1 | |
| SCHEMBL8083488 | 0.81 | MMP8 (0.45) | SPHK1EPHX2MMP8F2HPGD | |
| SCHEMBL8091412 | 0.79 | ALDH1A1 (0.34) | F2PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |