SCHEMBL8095086

SCHEMBL8095086

O=P(O)(O)C(Cc1cn(O)cn1)P(=O)(O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 14/20 0.49
GGPS1 O95749 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60911 0.70 CYP1A2 (0.45)
SCHEMBL14798187 0.70 CYP1A2 (0.45)
Hydrochloric Acid SCHEMBL6697015 0.69 TYR (0.45)
SCHEMBL8095105 0.66 FDPS (0.39) FDPSGGPS1
Piridronic Acid SCHEMBL223779 0.66 FDPS (1.00) FDPS
SCHEMBL9715316 0.66 FDPS (0.50) FDPSGGPS1
SCHEMBL9441323 0.66 FDPS (0.59) FDPSGGPS1
SCHEMBL6743060 0.64 FDPS (0.45) FDPSGGPS1
SCHEMBL9715271 0.63 FDPS (0.40) FDPSGGPS1
SCHEMBL8778299 0.62 FDPS (0.54) FDPSGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1057488-A1 INTERLEUKIN-6 PRODUCTION INHIBITORS TORAY INDUSTRIES, INC. (JP) 2000-12-06 EP claimed