Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624811 | 0.82 | FDPS (0.37) | FDPSANPEP | |
| SCHEMBL27472695 | 0.79 | PGK1 (0.45) | — | |
| SCHEMBL9459664 | 0.78 | FDPS (0.34) | FDPS | |
| Histidinol SCHEMBL1392278 | 0.76 | LAP3 (0.34) | LAP3ANPEP | |
| SCHEMBL9459999 | 0.76 | FDPS (0.33) | FDPS | |
| SCHEMBL8843726 | 0.76 | — | — | |
| Histidine SCHEMBL503658 | 0.75 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL28923637 | 0.75 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL503659 | 0.75 | SLC7A5 (0.43) | — | |
| Histidine SCHEMBL15670767 | 0.75 | SLC7A5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275821-A1 | Substituted alkanediphosphonic acids | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | claimed |
| EP-0275821-B1 | SUBSTITUTED ALKANEDIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1992-02-26 | — | — | EP | disclosed |
| US-4777163-A | BONE DISORDERS, RHEUMATIC DISEASES | BOEHRINGER MANNHEIM GMBH (DE) | 1988-10-11 | — | — | US | disclosed |
| EP-0275821-A1 | Substituted alkanediphosphonic acids | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | disclosed |