Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103045 | 0.86 | RBP4 (0.63) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL8095097 | 0.84 | GPR119 (0.53) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL71246 | 0.84 | EPHX2 (0.56) | GPR119KDM1ARBP4KDM4E | |
| SCHEMBL19839235 | 0.82 | PDE4B (0.64) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL5098530 | 0.80 | KDM1A (0.55) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL21765007 | 0.80 | KDM1A (0.57) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL74564 | 0.80 | KDM1A (0.57) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL3111017 | 0.79 | RBP4 (0.57) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL7406792 | 0.79 | KDM1A (0.50) | GPR119KDM1APDE4BPDE4APDE4C | |
| SCHEMBL69206 | 0.79 | KDM1A (0.56) | GPR119KDM1APDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |