Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102746 | 0.94 | KMT2A (0.45) | KMT2AKCNJ1KCNH2ALDH1A1HRH2 | |
| SCHEMBL8102735 | 0.94 | KMT2A (0.45) | KMT2AKCNJ1KCNH2ALDH1A1HRH2 | |
| SCHEMBL8104461 | 0.94 | KMT2A (0.45) | KMT2AKCNJ1KCNH2ALDH1A1HRH2 | |
| SCHEMBL8588975 | 0.94 | KMT2A (0.45) | KMT2AKCNJ1KCNH2ALDH1A1HRH2 | |
| SCHEMBL8104577 | 0.88 | DPP8 (0.36) | KMT2AKCNJ1KCNH2ALDH1A1GAA | |
| SCHEMBL8095116 | 0.84 | DPP8 (0.42) | KMT2AALDH1A1LMNASMN1; SMN2DPP8 | |
| SCHEMBL10701426 | 0.84 | RAB9A (0.40) | ALDH1A1HPGDMAPTDPP8DPP9 | |
| SCHEMBL8102914 | 0.84 | DPP8 (0.37) | KMT2AKCNJ1KCNH2ALDH1A1MAPT | |
| SCHEMBL8102893 | 0.84 | DPP8 (0.37) | KMT2AKCNJ1KCNH2ALDH1A1MAPT | |
| SCHEMBL8110594 | 0.84 | CCR5 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |