Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095285 | 0.74 | HRH3 (0.39) | MAPK1LMNAKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL30596603 | 0.70 | SMN1; SMN2 (0.60) | HPGDDUSP3GAAEPHX1MAPK1 | |
| SCHEMBL5897314 | 0.69 | HPGD (0.47) | HPGDDUSP3GAAEPHX1MAPK1 | |
| SCHEMBL22048302 | 0.68 | HRH3 (0.71) | HPGDDUSP3MAPK1KDM4EKEAP1 | |
| SCHEMBL17377315 | 0.68 | KEAP1 (0.62) | HPGDDUSP3KDM4EKEAP1SMN1; SMN2 | |
| SCHEMBL4042395 | 0.68 | KEAP1 (0.62) | HPGDDUSP3GAAMAPK1KDM4E | |
| SCHEMBL12937 | 0.68 | ALDH1A1 (0.54) | HPGDDUSP3KDM4EKEAP1SMN1; SMN2 | |
| SCHEMBL27494341 | 0.68 | HPGD (0.53) | HPGDDUSP3GAAMAPK1HIF1A | |
| SCHEMBL7161429 | 0.66 | PAOX (0.54) | HPGDDUSP3GAAEPHX1MAPK1 | |
| SCHEMBL8560572 | 0.66 | HRH3 (0.46) | HPGDDUSP3GAAEPHX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015814-A | Quinazoline derivative | ZENECA LIMITED (GB) | 2000-01-18 | — | — | US | disclosed |