Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090161 | 0.87 | SPHK1 (0.33) | SPHK2SPHK1F10CCR1 | |
| SCHEMBL8095316 | 0.87 | SMN1; SMN2 (0.43) | F10SMN1; SMN2NAMPTPOLBCCR1 | |
| SCHEMBL8091514 | 0.79 | F2 (0.38) | SPHK2SPHK1F10SMN1; SMN2PRSS1 | |
| SCHEMBL8091516 | 0.79 | F2 (0.38) | SPHK2SPHK1F10SMN1; SMN2PRSS1 | |
| SCHEMBL8083447 | 0.78 | SPHK1 (0.33) | SPHK2SPHK1F10 | |
| SCHEMBL8083409 | 0.77 | F10 (0.34) | SPHK2SPHK1F10SMN1; SMN2PRSS1 | |
| SCHEMBL8097998 | 0.77 | SPHK1 (0.35) | SPHK2SPHK1F10 | |
| SCHEMBL8083411 | 0.76 | F10 (0.34) | F10PRSS1 | |
| SCHEMBL8098085 | 0.76 | SPHK1 (0.33) | SPHK2SPHK1F10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8090129 | 0.76 | ALDH1A1 (0.34) | SPHK2SPHK1F10ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |