Diphenylether

Diphenylether

SCHEMBL8095335

CO.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.80
TSHR P16473 1/20 0.80
NR1H2 P55055 1/20 0.65
BAX Q07812 1/20 0.65
MAOA P21397 1/20 0.57
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA4 P22748 1/20 0.53
PARP10 Q53GL7 1/20 0.52
HPGD P15428 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SRD5A2 P31213 1/20 0.50
MAOB P27338 1/20 0.50
AKR1C3 P42330 1/20 0.50
PTGS1 P23219 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL11481331 0.90 LTA4H (0.86) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL12286 0.89 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL4950525 0.89 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL9061108 0.89 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL2461810 0.89 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL8671677 0.89 LTA4H (0.63) LTA4HTSHRNR1H2BAXPARP10
Diphenylether SCHEMBL27384641 0.87 LTA4H (0.80) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL28254838 0.87 LTA4H (0.80) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL10597664 0.87 LTA4H (0.80) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL28846645 0.87 LTA4H (0.80) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101407475-A II type pyrethroid universal hapten compound and synthetic method thereof INST OF OIL CROPS RES CHINESE (CN) 2009-04-15 CN disclosed
US-6025113-A FOR PREPARING HIGHLY SENSITIVE NEGATIVE-WORKING PHOTOSENSITIVE MATERIAL DEVELOPABLE WITH ALKALINE AQUEOUS SOLUTION IN SHORT TIME WITH HIGH RESOLUTION HITACHI CHEMICAL COMPANY, LTD. (JP) 2000-02-15 US disclosed
US-4468523-A PALLADIUM, VANADIUM OXIDE, TITANIUM ATLANTIC RICHFIELD COMPANY (US) 1984-08-28 US disclosed