Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102498 | 0.93 | KDM2B (0.41) | KMT2AMEN1CHRM4KDM2B | |
| SCHEMBL8103823 | 0.93 | FNTA (0.43) | KMT2AMEN1CHRM4ACKR3 | |
| SCHEMBL8088938 | 0.90 | KDM4E (0.46) | KMT2AMEN1ACKR3 | |
| SCHEMBL8088210 | 0.90 | TSHR (0.40) | KMT2AMEN1SMN1; SMN2ACKR3 | |
| SCHEMBL8097852 | 0.90 | KDM4E (0.46) | KMT2AMEN1ACKR3 | |
| SCHEMBL8095399 | 0.90 | CYP3A4 (0.44) | KMT2AMEN1CHRM4SMN1; SMN2 | |
| SCHEMBL8095367 | 0.89 | KDM4E (0.45) | KMT2AMEN1ACKR3 | |
| SCHEMBL8098292 | 0.86 | ATM (0.38) | KMT2AMEN1CHRM4 | |
| SCHEMBL8088441 | 0.84 | ALDH1A1 (0.43) | KMT2AMEN1 | |
| SCHEMBL8095905 | 0.83 | GSK3B (0.38) | CHRM4KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0862435-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0862435-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997018813-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-05-29 | — | — | WO | disclosed |