Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 13/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195275 | 0.92 | CRHR1 (0.36) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9200905 | 0.91 | CRHR1 (0.36) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9192875 | 0.90 | KDM4E (0.35) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9198028 | 0.90 | CRHR1 (0.38) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9198886 | 0.90 | CRHR1 (0.35) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9196334 | 0.88 | CRHR1 (0.34) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9694856 | 0.88 | CRHR1 (0.34) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9198645 | 0.87 | PDE1B (0.37) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9200684 | 0.86 | CRHR1 (0.33) | CRHR1PDE1BSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9197845 | 0.85 | RPS6KB1 (0.40) | SMN1; SMN2KDM4ECCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000169310-A | ACARICIDE COMPOSITION | SUMITOMO CHEM CO LTD | 2000-06-20 | — | — | JP | disclosed |
| WO-1998014434-A1 | 4-SUBSTITUTED 5-CHLORO-6-ALKYLPYRIMIDINE COMPOUNDS, PROCESS FOR THE PREPARATION OF THEM, AND PESTICIDE OR ACARICIDE COMPOSITIONS CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1998-04-09 | — | — | WO | disclosed |
| EP-0323757-B1 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-4931455-A | Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |