Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 15/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195275 | 0.87 | CRHR1 (0.36) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL8095407 | 0.87 | CRHR1 (0.37) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL9200905 | 0.86 | CRHR1 (0.36) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL9197511 | 0.85 | CRHR1 (0.33) | PDE1BCRHR1KDM4ENPC1HPGD | |
| SCHEMBL9194030 | 0.85 | KDM4E (0.33) | PDE1BCRHR1KDM4E | |
| SCHEMBL9199144 | 0.85 | PDE1B (0.32) | PDE1BCRHR1KDM4ENPC1HPGD | |
| SCHEMBL9198028 | 0.85 | CRHR1 (0.38) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL9198886 | 0.85 | CRHR1 (0.35) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL9192875 | 0.85 | KDM4E (0.35) | PDE1BPDE1APDE1CCRHR1KDM4E | |
| SCHEMBL9196334 | 0.84 | CRHR1 (0.34) | PDE1BPDE1APDE1CCRHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323757-B1 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-4931455-A | Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0323757-A2 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1989-07-12 | — | — | EP | disclosed |