SCHEMBL8095421

SCHEMBL8095421

C=Cc1ccccc1Cc1cccc2c1[nH]c1ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.44
PIM1 P11309 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39
GABRE P78334 2/20 0.39
GABRA6 Q16445 2/20 0.39
GABRG1 Q8N1C3 2/20 0.39
GABRG3 Q99928 2/20 0.39
GABRQ Q9UN88 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11141346 0.85 KIF11 (0.57) KIF11GABRPGABRDGABRA1GABRB1
Pavettine SCHEMBL29450528 0.82 KIF11 (0.53) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL28686824 0.82 KIF11 (0.53) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL27511814 0.82 KIF11 (0.53) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL36138 0.82 KIF11 (0.53) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL11349640 0.80 KIF11 (0.52) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL9643901 0.80 KIF11 (0.52) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL10336589 0.80 KIF11 (0.52) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL11798972 0.80 KIF11 (0.52) KIF11PIM1PIM3PIM2GABRP
Pavettine SCHEMBL28252142 0.80 ALDH1A1 (0.52) KIF11PIM1PIM3PIM2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017681-A EDGE JOINING OPTICAL PARTS BY APPLYING PHOTOSENSITIVE ADHESIVE TO SEPARATE EDGES AND IRRADIATING TO FORM WAVEGUIDES, THEN MATING EDGES AND HEATING TO MELT AND FUSE WAVEGUIDE MATERIAL FUJITSU LIMITED (JP) 2000-01-25 US disclosed
US-5902715-A FORMING A MIRROR-FINISHED SURFACE AT A BOUNDARY BETWEEN A AN IRRADIATED AND A NON-IRRADIATED WAVEGUIDE BY OBLIQUELY IRRADIATING THE WAVEGUIDE; REFRACTIVE INDEX MAY BE INCREASED BY HEATING IRRADIATED PORTION, OR WITH A CATALYZER FUJITSU LIMITED (JP) 1999-05-11 US disclosed
US-5861444-A COPOLYMER BINDER, PHOTOSENSITIVE MONOMER, PHOTOPOLYMERIZATION INITIATOR FUJITSU LIMITED (JP) 1999-01-19 US disclosed
US-5658966-A Method of coupling optical parts and refractive index imaging material FUJITSU LIMITED (JP) 1997-08-19 US disclosed
US-5581646-A Method of coupling optical parts and refractive index imaging material FUJITSU LIMITED (JP) 1996-12-03 US disclosed