SCHEMBL8095449

SCHEMBL8095449

C=C(C)C(=O)OCCC1=CC=C2C(=Nc3ccccc32)C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
HTT P42858 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
THRB P10828 1/20 0.33
TSHR P16473 3/20 0.33
LMNA P02545 3/20 0.32
MAPT P10636 3/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSP90AA1 P07900 2/20 0.32
APAF1 O14727 1/20 0.32
HSP90AB1 P08238 1/20 0.32
HK1 P19367 1/20 0.32
GALK1 P51570 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23648353 0.66 THRB (0.49) TDP1HTTPOLBAPEX1THRB
SCHEMBL1269638 0.66 CA12 (0.55) TDP1HTTPOLBAPEX1THRB
SCHEMBL28746696 0.66 MAPT (0.39) TDP1TSHRLMNAMAPTALDH1A1
SCHEMBL31087892 0.65 CDK2 (0.34) TDP1TSHRLMNAMAPTALDH1A1
SCHEMBL42893 0.65 HCAR2 (0.51) TDP1HTTPOLBAPEX1THRB
SCHEMBL1938350 0.64 THRB (0.46) TDP1HTTPOLBAPEX1THRB
SCHEMBL15713250 0.64 TSHR (0.53) TDP1HTTPOLBAPEX1THRB
SCHEMBL13515784 0.64 GAA (0.57) TDP1HTTPOLBAPEX1THRB
SCHEMBL27459251 0.64 KMT2A (0.44) TDP1HTTPOLBAPEX1THRB
SCHEMBL14848425 0.64 THRB (0.40) TDP1HTTPOLBAPEX1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017681-A EDGE JOINING OPTICAL PARTS BY APPLYING PHOTOSENSITIVE ADHESIVE TO SEPARATE EDGES AND IRRADIATING TO FORM WAVEGUIDES, THEN MATING EDGES AND HEATING TO MELT AND FUSE WAVEGUIDE MATERIAL FUJITSU LIMITED (JP) 2000-01-25 US disclosed
US-5902715-A FORMING A MIRROR-FINISHED SURFACE AT A BOUNDARY BETWEEN A AN IRRADIATED AND A NON-IRRADIATED WAVEGUIDE BY OBLIQUELY IRRADIATING THE WAVEGUIDE; REFRACTIVE INDEX MAY BE INCREASED BY HEATING IRRADIATED PORTION, OR WITH A CATALYZER FUJITSU LIMITED (JP) 1999-05-11 US disclosed
US-5861444-A COPOLYMER BINDER, PHOTOSENSITIVE MONOMER, PHOTOPOLYMERIZATION INITIATOR FUJITSU LIMITED (JP) 1999-01-19 US disclosed
US-5658966-A Method of coupling optical parts and refractive index imaging material FUJITSU LIMITED (JP) 1997-08-19 US disclosed
US-5581646-A Method of coupling optical parts and refractive index imaging material FUJITSU LIMITED (JP) 1996-12-03 US disclosed