Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.84 |
| ▸ | CA4 | P22748 | 2/20 | 0.84 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL394354 | 0.97 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL14629920 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL9824758 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL2772100 | 0.94 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL841158 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL2413021 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL5865919 | 0.94 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL21220126 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL21633524 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11864285 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654630-B | Tetradentate diaminodiphosphine ligands, transition metal complexes, methods for their production and use thereof | 高砂香料工业株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-112654630-A | Tetradentate diamino diphosphine ligand, transition metal complex, their production method and use | 高砂香料工业株式会社 | 2021-04-13 | — | — | CN | disclosed |
| CN-111886932-A | Inorganic EL element, display element, image display device, and system | 株式会社理光 | 2020-11-03 | — | — | CN | disclosed |
| CN-100507101-C | Copolyesters and fibrous materials formed therefrom | EASTMAN CHEM CO (US) | 2009-07-01 | — | — | CN | disclosed |
| CN-1167836-C | Copolyester binder fibers | �Ϻ���ͨ��ѧ | 2004-09-22 | — | — | CN | disclosed |
| CN-1429290-A | Copolyesters and fibrous materials formed therefrom | EASTMAN CHEM CO (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1377380-A | Polyesters having a controlled melting point and fibers formed therefrom | EASTMAN CHEM CO (US) | 2002-10-30 | — | — | CN | disclosed |
| CN-1330735-A | Copolyester binder fibers | EASTMAN CHEMICAL BO (US) | 2002-01-09 | — | — | CN | disclosed |
| CN-1324415-A | Polyesters contg. neopentyl glycol and fibers formed therefrom | EASTMAN CHEM CO (US) | 2001-11-28 | — | — | CN | disclosed |
| EP-0702249-B1 | Plastic optical material and production process thereof | KUREHA CHEMICAL IND CO LTD (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5672655-A | COPOLYMERIZING PHOSPHATE CONTAINING ACRYLIC OR METHACRYLIC ESTER MONOMER WITH ATLEAST ONE COPOLYMERIZING MONOMER AND A METAL ION COMPONENT CONTAINING NEODYMINUM ION AND ONE ANOTHER METAL ION; LESNES OR SUNGLASSES; GLARE-PROOFING | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-30 | — | — | US | disclosed |
| CN-1121727-A | Copolyester of cyclohexanedimethanol and process for producing such polyester | EASTMAN CHEM CO (US) | 1996-05-01 | — | — | CN | disclosed |
| EP-0702249-A1 | Plastic optical material and production process thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-3962189-A | PROCESS AND CATALYST-INHIBITOR SYSTEMS FOR PREPARING SYNTHETIC LINEAR POLYESTERS | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | disclosed |