Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.84 |
| ▸ | CA4 | P22748 | 2/20 | 0.84 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL21633524 | 1.00 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11864285 | 1.00 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL186964 | 0.97 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL8671976 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL10340353 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL28481704 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL28569088 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29027326 | 0.94 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL5865919 | 0.94 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL21220126 | 0.94 | CA2 (0.84) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10125081-B2 | Method for producing carboxylic acid anhydride and method for producing carboxylic acid ester | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-11-13 | — | — | US | claimed |
| US-5540866-A | CLEANING, DEGREASING | COLGATE-PALMOLIVE CO. (US) | 1996-07-30 | — | — | US | claimed |
| US-4923635-A | Liquid detergent composition containing alkylbenzene sulfonate, alkyl ethanol ether sulfate, alkanolamide foam booster and magnesium and triethanolammonium ions | COLGATE-PALMOLIVE COMPANY (US) | 1990-05-08 | — | — | US | claimed |
| EP-3381895-B1 | METHOD FOR PRODUCING CARBOXYLIC ACID THIOESTER | MITSUBISHI CHEM CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| CN-106572957-B | Skin color improving agent and composition for improving skin color | 昭和电工株式会社 | 2020-03-27 | — | — | CN | disclosed |
| EP-3185850-B1 | SKIN COLOR-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN COLOR | SHOWA DENKO KK (JP) | 2019-10-09 | — | — | EP | disclosed |
| EP-3235801-B1 | CARBOXYLIC ACID ESTER PRODUCTION METHOD | MITSUBISHI CHEM CORP (JP) | 2019-02-20 | — | — | EP | disclosed |
| US-10125081-B2 | Method for producing carboxylic acid anhydride and method for producing carboxylic acid ester | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-3381895-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID THIOESTER | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-10-03 | — | — | EP | disclosed |
| EP-2767570-B1 | Reaction material and chemical heat pump | RICOH CO LTD (JP) | 2018-04-04 | — | — | EP | disclosed |
| EP-3153495-B1 | METHOD FOR PRODUCING CARBOXYLIC ACID ANHYDRIDE, AND METHOD FOR PRODUCING CARBOXYLIC ACID ESTER | MITSUBISHI CHEM CORP (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-20030064206-A1 | Pretreatment liquid for recording material and image recording method using the pretreatment liquid | RICOH COMPANY LIMITED (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1243435-A1 | Pretreatment liquid for recording material and image recording method using the pretreatment liquid | Ricoh Company, Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0739743-B1 | Ink jet recording method | SEIKO EPSON CORP (JP) | 2002-02-06 | — | — | EP | disclosed |
| US-6286953-B1 | Ink jet recording method | SEIKO EPSON CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0739743-A1 | Ink jet recording method | SEIKO EPSON CORPORATION (JP) | 1996-10-30 | — | — | EP | disclosed |
| US-5540866-A | CLEANING, DEGREASING | COLGATE-PALMOLIVE CO. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5096622-A | Liquid detergent composition containing alkylbenzene sulfonate, alkyl ethonal ether sulfate, alkanolamide foam booster and magnesium and triethanolammonium ions | COLGATE-PALMOLIVE COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4923635-A | Liquid detergent composition containing alkylbenzene sulfonate, alkyl ethanol ether sulfate, alkanolamide foam booster and magnesium and triethanolammonium ions | COLGATE-PALMOLIVE COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-3984389-A | Process for the polymerization of olefins and catalytic products | SOLVAY & CIE (BE) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10125081-B2 | Method for producing carboxylic acid anhydride and method for producing carboxylic acid ester | CA1, CA12, CA6 | CA2 6/4885CA4 7/4885CES1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.