Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211346 | 0.85 | MAPT (0.46) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL8087032 | 0.84 | KDM4E (0.57) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7800014 | 0.83 | TPMT (0.41) | ALDH1A1MAPTKDM4ETP53HTT | |
| SCHEMBL13495880 | 0.82 | ALDH1A1 (0.50) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6296289 | 0.81 | KDM4E (0.43) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL3549964 | 0.81 | MAPT (0.51) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL30037411 | 0.81 | MAPT (0.51) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL8101046 | 0.79 | HPGD (0.58) | HPGDALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL20803216 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL31363552 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030952-A | AS HUMAN AND VETERINARY MEDICINE, PARTICULARLY IN THE TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR AND OPHTHALMOLOGIC CONDITIONS, AND IN COSMETIC COMPOSITIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES GALDERMA (FR) | 2000-02-29 | — | — | US | disclosed |