Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20803216 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL4289129 | 0.88 | CA12 (0.38) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL13159061 | 0.84 | CYP46A1 (0.44) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL2467212 | 0.82 | NR4A2 (0.43) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL9221122 | 0.82 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL13159056 | 0.82 | ABL1 (0.49) | ALDH1A1KDM4EHPGDL3MBTL1MAPT | |
| SCHEMBL9857862 | 0.82 | KDM4E (0.40) | ALDH1A1HSD17B10KDM4EHPGDPDK2 | |
| SCHEMBL11165984 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL28987574 | 0.78 | HSD17B10 (0.54) | ALDH1A1HSD17B10KDM4EHPGDCA2 | |
| SCHEMBL7281224 | 0.78 | MDH1 (0.40) | CA2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |