Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.69 |
| ▸ | CNR2 | P34972 | 4/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086461 | 0.95 | CNR1 (0.61) | CNR1CNR2PTGS1PTGS2CA12 | |
| SCHEMBL8086096 | 0.91 | CNR1 (0.69) | CNR1CNR2PTGS1PTGS2 | |
| SCHEMBL8093875 | 0.91 | CNR1 (0.64) | CNR1CNR2PTGS1PTGS2CA12 | |
| SCHEMBL8093740 | 0.89 | CNR1 (0.60) | CNR1CNR2PTGS1PTGS2CA12 | |
| SCHEMBL8095103 | 0.85 | CNR1 (0.61) | CNR1CNR2PTGS1PTGS2 | |
| SCHEMBL8094678 | 0.85 | SQOR (0.53) | CNR1CNR2PTGS2ALDH1A1 | |
| SCHEMBL8094551 | 0.84 | CNR1 (0.49) | CNR1CNR2PTGS1PTGS2CA12 | |
| SCHEMBL8094187 | 0.84 | CNR1 (0.50) | CNR1CNR2PTGS2CA12CA1 | |
| SCHEMBL8101417 | 0.83 | CNR1 (0.50) | CNR1CNR2PTGS1PTGS2CA12 | |
| SCHEMBL8095521 | 0.82 | CNR1 (0.52) | CNR1PTGS1PTGS2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |