Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356171 | 0.83 | GABRP (0.41) | ALDH1A1LMNA | |
| SCHEMBL11143865 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL10434717 | 0.81 | TDP1 (0.36) | TDP1 | |
| SCHEMBL27958764 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8095838 | 0.78 | MAPT (0.34) | — | |
| SCHEMBL27676114 | 0.78 | TSHR (0.44) | ALDH1A1LMNA | |
| SCHEMBL17260751 | 0.77 | — | — | |
| SCHEMBL6670794 | 0.77 | AKR1B1 (0.43) | ALDH1A1LMNATDP1 | |
| SCHEMBL27423467 | 0.76 | — | — | |
| SCHEMBL27604881 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020488-A | Small molecule inhibition of RNA/ligand binding | SCRIPTGEN PHARMACEUTICALS INC. (US) | 2000-02-01 | — | — | US | claimed |
| EP-0833824-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1996040668-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-6020488-A | Small molecule inhibition of RNA/ligand binding | SCRIPTGEN PHARMACEUTICALS INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0833824-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5668165-A | TREATMENT OF HIV INFECTIONS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040668-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |