SCHEMBL8095886

SCHEMBL8095886

CCCCCCCOC(=O)c1cc[c]cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
NPC1 O15118 1/20 0.67
MAPT P10636 1/20 0.67
RAB9A P51151 1/20 0.67
LMNA P02545 4/20 0.58
TSHR P16473 4/20 0.58
ESR1 P03372 4/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 2/20 0.58
MAPK1 P28482 2/20 0.58
CYP2D6 P10635 1/20 0.58
NR1H2 P55055 1/20 0.58
RNASEL Q05823 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
AKR1C4 P17516 1/20 0.58
AKR1C3 P42330 1/20 0.58
AKR1C2 P52895 1/20 0.58
AKR1C1 Q04828 1/20 0.58
STS P08842 6/20 0.57
CYP3A4 P08684 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3225675 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL3262610 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL3221420 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL710852 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL6412993 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL1310680 1.00 ALDH1A1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL1312058 0.98 ALDH1A1 (0.64) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL131778 0.93 ESR1 (0.67) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL108412 0.88 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ALMNA
SCHEMBL10591672 0.88 ALDH1A1 (0.83) ALDH1A1NPC1MAPTRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060226-A1 LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-12-20 EP disclosed
WO-1999043763-A1 LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS THE SECRETARY OF STATE FOR DEFENCE (GB) 1999-09-02 WO disclosed
US-5248778-A POLYALKYLPIPERIDINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1993-09-28 US disclosed
EP-0481300-A2 Polyalkylpiperidine-derivatives and their use as light stabilizers BASF Aktiengesellschaft (DE) 1992-04-22 EP disclosed