Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734639 | 0.91 | SIGMAR1 (0.47) | SIGMAR1TP53TSHRALDH1A1HPGD | |
| SCHEMBL18863923 | 0.88 | SIGMAR1 (0.41) | SIGMAR1TP53TSHRPOLBANPEP | |
| SCHEMBL13765586 | 0.88 | TDP1 (0.45) | SIGMAR1TSHRHPGDPOLBANPEP | |
| SCHEMBL23019660 | 0.87 | MAOA (0.50) | SIGMAR1TAAR1 | |
| SCHEMBL8101237 | 0.87 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1 | |
| SCHEMBL28322341 | 0.87 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1 | |
| SCHEMBL28294365 | 0.86 | TSHR (0.41) | SIGMAR1TSHRALDH1A1POLBERAP1 | |
| SCHEMBL8095818 | 0.85 | SIGMAR1 (0.52) | SIGMAR1HPGD | |
| SCHEMBL27183167 | 0.84 | KDM4E (0.42) | SIGMAR1ALDH1A1 | |
| SCHEMBL8100431 | 0.84 | TP53 (0.46) | SIGMAR1TP53TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |