Uracil

Uracil

SCHEMBL80962

O=c1nc(O)cc[nH]1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL27846109 0.98
Cytosine SCHEMBL1330710 0.75
Cytosine SCHEMBL1330400 0.75
Cytosine SCHEMBL4657334 0.75 DYRK1A (0.44)
Cytosine SCHEMBL4059 0.75
Cytosine SCHEMBL19692377 0.73
Cytosine SCHEMBL20212017 0.73
Cytosine SCHEMBL10623341 0.73
Cytosine SCHEMBL21772310 0.73 DYRK1A (0.42)
Cytosine SCHEMBL4065266 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230266670-A1 METAL CHELATORS FOR DEVELOPMENT OF METAL-CONTAINING PHOTORESIST LAM RESEARCH CORPORATION 2023-08-24 US claimed
CN-116134383-A Metal chelators for development of metal-containing photoresists 朗姆研究公司 2023-05-16 CN claimed
WO-2022016126-A1 METAL CHELATORS FOR DEVELOPMENT OF METAL-CONTAINING PHOTORESIST LAM RESEARCH CORPORATION (US) 2022-01-20 WO claimed
US-8475768-B2 Paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (MRI) GE HEALTHCARE AS (NO) 2013-07-02 US claimed
US-8222412-B2 Preparation of aminopyrimidine compounds ASTRAZENECA UK LIMITED (GB) 2012-07-17 US claimed
CN-101914067-B Method for synthesizing N-methyl pyrimidone DAILING CHEN 2012-07-11 CN claimed
US-20110200536-A1 CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2011-08-18 US claimed
US-20110160455-A1 Preparation of Aminopyrimidine Compounds ASTRAZENECA UK LTD. (GB) 2011-06-30 US claimed
US-20110110865-A1 CHELATROS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2011-05-12 US claimed
CN-101914067-A Method for synthesizing N-methyl pyrimidone DAILING CHEN 2010-12-15 CN claimed
WO-2009021948-A1 CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2009-02-19 WO claimed
WO-2009021947-A1 CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2009-02-19 WO claimed
US-20080159954-A1 METAL CHELATES HAVING A PERFLUORINATED PEG RADICAL, PROCESSES FOR THEIR PREPARATION, AND THEIR USE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2008-07-03 US claimed
WO-2008046463-A1 METAL CHELATES HAVING A PERFLUORINATED PEG GROUP, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-24 WO claimed
EP-1417180-A4 PREPARATION OF AMINOPYRIMIDINE COMPOUNDS ASTRAZENECA UK LTD (GB) 2004-10-27 EP claimed
US-20040176401-A1 Preparation of aminopyrimidine compounds ASTRAZENECA UK LIMITED (GB) 2004-09-09 US claimed
EP-1417180-A1 PREPARATION OF AMINOPYRIMIDINE COMPOUNDS Astrazeneca UK Limited (GB) 2004-05-12 EP claimed
WO-2003006439-A1 PREPARATION OF AMINOPYRIMIDINE COMPOUNDS ASTRAZENECA UK LIMITED (GB) 2003-01-23 WO claimed
US-5889184-A Process for pyrimidinone compounds PRINCETON UNIVERSITY (US) 1999-03-30 US claimed
EP-0812832-A1 Improved process for pyrimidinone compounds ROHM AND HAAS COMPANY (US) 1997-12-17 EP claimed