Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859068 | 0.76 | INMT (0.39) | INMTUSP2 | |
| SCHEMBL6860529 | 0.71 | INMT (0.47) | INMTUSP2 | |
| SCHEMBL6859941 | 0.69 | INMT (0.50) | INMTUSP2 | |
| SCHEMBL9511532 | 0.68 | SLC18A3 (0.39) | USP2 | |
| SCHEMBL17956740 | 0.66 | INMT (0.46) | INMTUSP2 | |
| SCHEMBL2927 | 0.64 | — | — | |
| SCHEMBL17417845 | 0.64 | — | — | |
| SCHEMBL22192848 | 0.64 | INMT (0.44) | INMTUSP2HRH4 | |
| SCHEMBL21122272 | 0.64 | INMT (0.43) | INMTUSP2 | |
| SCHEMBL22193156 | 0.63 | INMT (0.59) | INMTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476175-B2 | REACTING LACTONE WITH DIAMINE BY HEATING; POLYURETHANE POLYMERIZATION CATALYST | LONZA LTD. (CH) | 2002-11-05 | — | — | US | claimed |
| US-20020028939-A1 | Bicyclic amidines, process for their preparation, and their use as catalyst | WERBITZKY OLEG (CH) | 2002-03-07 | — | — | US | claimed |
| EP-0869127-B1 | Bicyclic amidines and their use as catalysts | LONZA AG (CH) | 2001-10-10 | — | — | EP | claimed |
| US-5922869-A | CATALYSTS FOR SYNTHESIS OF POLYURETHANES WHICH ARE BONDED SO FIRMLY TO THE POLYMER THEY NO LONGER DIFFUSE OUT OF OR ARE EXTRACTED FROM THE POLYURETHANE, PREVENTS UNNEXESSARY POLLUTION OF THE ENVIRONMENT | LONZA LTD. (CH) | 1999-07-13 | — | — | US | claimed |
| EP-0869127-A1 | Bicyclic amidines and their use as catalysts | LONZA AG (CH) | 1998-10-07 | — | — | EP | claimed |
| EP-0662476-A1 | Bicyclic amidines, process for their preparation and their use as catalysts | LONZA AG (CH) | 1995-07-12 | — | — | EP | claimed |
| EP-2098567-B1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | DENKI KAGAKU KOGYO KK (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-8012556-B2 | Acrylic rubber composition and its vulcanized product | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100009105-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZED PRODUCT | DENKI KAGAKU KIGYO KABUSHIKI KAISHA (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2098567-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | Denki Kagaku Kogyo Kabushiki Kaisha (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-6476175-B2 | REACTING LACTONE WITH DIAMINE BY HEATING; POLYURETHANE POLYMERIZATION CATALYST | LONZA LTD. (CH) | 2002-11-05 | — | — | US | disclosed |
| EP-0662476-B2 | Process for the preparation of bicyclic amidines | LONZA AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| US-20020028939-A1 | Bicyclic amidines, process for their preparation, and their use as catalyst | WERBITZKY OLEG (CH) | 2002-03-07 | — | — | US | disclosed |
| EP-0869127-B1 | Bicyclic amidines and their use as catalysts | LONZA AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| US-6255488-B1 | BICYCLIC AMIDINES HAVING AMINO, HYDROXYL, AND/OR MERCAPTO GROUPS USEFUL AS CATALYSTS FOR PREPARATION OF POLYURETHANES; WHICH BOND FIRMLY TO THE POLYMER WITH NO TENDENCY TOWARDS MIGRATION | LONZA AG (CH) | 2001-07-03 | — | — | US | disclosed |
| US-5922869-A | CATALYSTS FOR SYNTHESIS OF POLYURETHANES WHICH ARE BONDED SO FIRMLY TO THE POLYMER THEY NO LONGER DIFFUSE OUT OF OR ARE EXTRACTED FROM THE POLYURETHANE, PREVENTS UNNEXESSARY POLLUTION OF THE ENVIRONMENT | LONZA LTD. (CH) | 1999-07-13 | — | — | US | disclosed |
| EP-0662476-B1 | Process for the preparation of bicyclic amidines | LONZA AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| EP-0869127-A1 | Bicyclic amidines and their use as catalysts | LONZA AG (CH) | 1998-10-07 | — | — | EP | disclosed |
| US-5723605-A | Bicyclic amidines, process for their preparation, and their use as catalyst | LONZA LTD. (CH) | 1998-03-03 | — | — | US | disclosed |
| EP-0662476-A1 | Bicyclic amidines, process for their preparation and their use as catalysts | LONZA AG (CH) | 1995-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028939-A1 | Bicyclic amidines, process for their preparation, and their use as catalyst | CBR1, CBR3, RER1 | INMT 1116/4885USP2 3077/4885HRH4 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.