Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111450 | 0.83 | SLC6A4 (0.41) | NOS3NOS1NOS2TAAR1 | |
| SCHEMBL8393622 | 0.77 | SLC6A4 (0.41) | — | |
| SCHEMBL2096002 | 0.77 | NOS3 (0.46) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL8091958 | 0.76 | NOS3 (0.41) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL8109498 | 0.76 | NOS3 (0.41) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL1830037 | 0.75 | NOS3 (0.50) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL8395888 | 0.73 | CHRNA7 (0.41) | MAOB | |
| SCHEMBL52608 | 0.71 | NOS3 (0.54) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL5654987 | 0.71 | NOS3 (0.54) | NOS3NOS1NOS2TAAR1GBA1 | |
| SCHEMBL8086082 | 0.70 | TACR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |