Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111409 | 0.87 | LMNA (0.60) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8140791 | 0.82 | MGLL (0.62) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8149182 | 0.80 | MGLL (0.67) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8105526 | 0.80 | MGLL (0.58) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL4670619 | 0.79 | MGLL (0.55) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8109771 | 0.79 | KMT2A (0.69) | MGLLMEN1KMT2ALMNAHSD11B1 | |
| SCHEMBL8106361 | 0.79 | LMNA (0.58) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL4671313 | 0.79 | MGLL (0.58) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8109746 | 0.79 | MGLL (0.58) | MGLLMEN1KMT2ALMNATP53 | |
| SCHEMBL8154882 | 0.79 | MGLL (0.43) | MGLLMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |