Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233246 | 1.00 | TSHR (0.44) | TSHRKMT2AMEN1TET2THRB | |
| SCHEMBL8102884 | 0.98 | TSHR (0.46) | TSHRKMT2AMEN1TET2LMNA | |
| SCHEMBL24065971 | 0.84 | TSHR (0.42) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL22118494 | 0.82 | ALDH1A1 (0.36) | THRBGBA1ALDH1A1 | |
| SCHEMBL9854290 | 0.81 | TRPA1 (0.41) | TSHRKMT2ALMNAKDM4EHSD17B10 | |
| SCHEMBL9854447 | 0.81 | TRPA1 (0.41) | TSHRKMT2ALMNAKDM4EHSD17B10 | |
| SCHEMBL28039689 | 0.80 | ALDH1A1 (0.33) | THRBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL29278779 | 0.80 | TSHR (0.37) | TSHRTET2THRBCA12CA14 | |
| SCHEMBL29278786 | 0.80 | TSHR (0.37) | TSHRTET2THRBCA12CA14 | |
| SCHEMBL12765425 | 0.80 | TSHR (0.36) | TSHRKMT2AMEN1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054615-A | Fluorinated quaternary ammonium salts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-25 | — | — | US | disclosed |