SCHEMBL8096693

SCHEMBL8096693

CCC(C)CC(C)=O.CCCC(=O)CC(C)C

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP2C19 P33261 1/20 0.33
CA2 P00918 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
ACHE P22303 1/20 0.30
FFAR3 O14843 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107545 0.83 CES2 (0.39) ALDH1A1CA2CES2CES1FFAR3
SCHEMBL104701 0.83
Methyl Isobutyl Ketone SCHEMBL22321104 0.81 ALDH1A1 (0.67) ALDH1A1TDP1CYP2C19CA2CES2
SCHEMBL7540967 0.81
SCHEMBL27601579 0.81
SCHEMBL4984202 0.81
SCHEMBL270159 0.81
SCHEMBL28649278 0.77 ALDH1A1 (0.52) ALDH1A1TDP1CYP2C19CA2CES2
SCHEMBL7520831 0.77 CYP2C19 (0.46) ALDH1A1TDP1CYP2C19CA2CES2
SCHEMBL107548 0.77 CYP2C19 (0.46) ALDH1A1TDP1CYP2C19CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984683-A2 MEANS AMD METHOD FOR PEST CONTROL OCTROOIBUREAU KISCH N.V. (AN) 2000-03-15 EP disclosed
WO-1998053678-A2 MEANS AMD METHOD FOR PEST CONTROL OCTROOIBUREAU KISCH N. V. (AN) 1998-12-03 WO disclosed