SCHEMBL8096749

SCHEMBL8096749

O=C(O)C[C@H](NCCOCCN[C@@H](CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GGT1 P19440 1/20 0.34
MME P08473 2/20 0.34
TSHR P16473 1/20 0.34
SUCNR1 Q9BXA5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29896405 0.98 CA2 (0.38) CA2CA4TDP1SMN1; SMN2MEN1
SCHEMBL29896413 0.98 CA2 (0.38) CA2CA4TDP1SMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL29896376 0.96 CA2 (0.37) CA2CA4TDP1SMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL29896429 0.96 CA2 (0.37) CA2CA4TDP1SMN1; SMN2MEN1
SCHEMBL29896387 0.91 FOLH1 (0.35) CA2CA4SMN1; SMN2MEN1KMT2A
SCHEMBL29010081 0.88 CA2 (0.33) CA2CA4MEN1KMT2ASUCNR1
Trifluoroacetic Acid SCHEMBL29896394 0.88 TMPRSS15 (0.35) CA2CA4MEN1KMT2ATSHR
SCHEMBL15637714 0.84 CA2 (0.45) CA2CA4TDP1SMN1; SMN2GGT1
SCHEMBL5825896 0.84 CA2 (0.45) CA2CA4TDP1SMN1; SMN2GGT1
SCHEMBL414800 0.84 CA2 (0.45) CA2CA4TDP1SMN1; SMN2GGT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0904263-B1 N-BIS- OR N-TRIS-[(1,2-DICARBOXY-ETHOXY)-ETHYL]-AMINE DERIVATIVES AND PREPARATION AND USE OF THE SAME KEMIRA CHEMICALS OY (FI) 2000-12-27 EP disclosed
US-6093849-A MADE BY REACTING DI- OR TRIETHANOLAMINE WITH A GROUP 1A OR 2A SALT OF MALEIC ACID IN THE PRESENCE OF A LANTHANIDE COMPOUND ALKYLATION CATALYST; USE AS CHELATING AGENTS; CHELATING HEAVY METALS PRIOR TO BLEACHING CELLULOSE PULP KEMIRA CHEMICALS OY (FI) 2000-07-25 US disclosed
EP-0904263-A1 N-BIS- OR N-TRIS- (1,2-DICARBOXY-ETHOXY)-ETHYL]-AMINE DERIVATIVES AND PREPARATION AND USE OF THE SAME KEMIRA CHEMICALS OY (FI) 1999-03-31 EP disclosed
WO-1997045396-A1 N-BIS- OR N-TRIS-[(1,2-DICARBOXY-ETHOXY)-ETHYL]-AMINE DERIVATIVES AND PREPARATION AND USE OF THE SAME KEMIRA CHEMICALS OY (FI) 1997-12-04 WO disclosed