Palmitic Acid

Palmitic Acid

SCHEMBL8096795

CC(O)C(=O)O.CCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1

The experimentally established mechanism targets of Palmitic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC11 known ✓ Q96DB2 5/20 0.74
PDE3A known ✓ Q14432 1/20 0.74
GPR84 Q9NQS5 7/20 0.74
PPARG P37231 7/20 0.74
PPARD Q03181 7/20 0.74
PPARA Q07869 7/20 0.74
TSHR P16473 4/20 0.74
PTPN1 P18031 3/20 0.74
ALDH1A1 P00352 2/20 0.74
TLR2 O60603 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
FABP4 P15090 2/20 0.74
FFAR1 O14842 2/20 0.74
FFAR4 Q5NUL3 2/20 0.74
KMT2A Q03164 2/20 0.74
ALOX15 P16050 2/20 0.74
HSD17B10 Q99714 2/20 0.74
SLC22A6 Q4U2R8 1/20 0.74
SLC22A8 Q8TCC7 1/20 0.74
MEN1 O00255 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Behenic Acid SCHEMBL27557897 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL27700306 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Heptanoate SCHEMBL29196949 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL8412450 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL27793546 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL1662973 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL8413830 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Nonanoate SCHEMBL29197328 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL1646803 1.00 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL8332921 0.98 GPR84 (0.71) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105595188-A Stable whippable and whipped food products RICH PRODUCTS CORP 2016-05-25 CN disclosed
EP-0711540-B1 Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation OREAL (FR) 2000-05-10 EP disclosed
EP-0711540-A1 Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation L'OREAL (FR) 1996-05-15 EP disclosed