Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Dodecanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.74 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.74 |
| ▸ | PPARG | P37231 | 7/20 | 0.74 |
| ▸ | PPARD | Q03181 | 7/20 | 0.74 |
| ▸ | PPARA | Q07869 | 7/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | TLR2 | O60603 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | FABP4 | P15090 | 2/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.74 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Behenic Acid SCHEMBL27557897 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL27700306 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL29196949 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL27793546 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1662973 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8413830 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL29197328 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL8096795 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL1646803 | 1.00 | GPR84 (0.74) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL8332921 | 0.98 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222313-A | Antimicrobial compositions | 联合利华知识产权控股有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-107759137-A | A kind of preparation method of mechanical foaming pitch warm mix regenerating mixture | 深圳市路桥建设集团有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-114569730-B | Felodipine transdermal enhancer combination, felodipine transdermal administration preparation and transdermal delivery device | 鑫稳生物医药科技(嘉善)有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117222313-A | Antimicrobial compositions | 联合利华知识产权控股有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-114569730-A | Felodipine transdermal drug delivery agent combination, felodipine transdermal drug delivery preparation and transdermal delivery device | 鑫稳生物医药科技(嘉善)有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-106309421-A | Medical compound and cosmetic compound | 沃凯索法株式会社 | 2017-01-11 | — | — | CN | disclosed |
| CN-104825554-A | Gouty arthritis treatment spraying agent | GUANGZHOU JINAN BIOMEDICINE RES & DEV CT CO LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-103800313-A | Novel derivatives of cyclic compound and the use thereof | WONKISOPHARM CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-101547886-B | pharmaceutical composition and cosmetic composition | WONKISOPHARM CO LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-101547886-A | Novel derivative of cyclic compound and use thereof | WONKISOPHARM CO LTD (KR) | 2009-09-30 | — | — | CN | disclosed |
| CN-101161802-A | Method for manufacturing polyglycerol compound (medium-carbon) fatty acid ester | JIANCHENG LI (CN) | 2008-04-16 | — | — | CN | disclosed |
| US-5872268-A | SUBJECTING A FATTY ACID ESTER OF LOWER ALCOHOL AND AN ALKALINE METAL SALT OR ALKALINE EARTH METAL SALT OF HYDROXYCARBOXYLIC ACID TO ESTER INTERCHANGE IN AN ORGANIC SOLVENT IN THE PRESENCE OF A NONIONIC OR ANIONIC SURFACE ACTIVE AGENT AND AN | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| US-4565635-A | GUM, POLYMER, OR BIOGUM MATERIAL AND WATER DONOR MATERIAL MIXTURE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-01-21 | — | — | US | disclosed |