Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GMNN | O75496 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26302871 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL18206743 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL28615131 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL30104620 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL8106034 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL11354234 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL1527349 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| Octane SCHEMBL3694961 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL6630577 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL26197073 | 1.00 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230304002-A1 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES | BANK OF AMERICA, N.A. | 2023-09-28 | — | — | US | disclosed |
| US-20230272382-A1 | COMPLEMENT COMPONENT C3 iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING COMPLEMENT COMPONENT C3-ASSOCIATED DISEASES | BANK OF AMERICA, N.A. | 2023-08-31 | — | — | US | disclosed |
| EP-0711540-B1 | Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation | OREAL (FR) | 2000-05-10 | — | — | EP | disclosed |
| EP-0711540-A1 | Cosmetic or dermatologic oil/water dispersion stabilized with cubic gel particles and method of preparation | L'OREAL (FR) | 1996-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230304002-A1 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES | TTR, MTPN, CRYAA | LMNA 86/4885MAPT 293/4885MAPK1 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.