Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17149399 | 0.82 | GAA (0.66) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL14354629 | 0.81 | LMNA (0.61) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4380684 | 0.80 | SMN1; SMN2 (0.57) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8100529 | 0.80 | LMNA (0.56) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11859468 | 0.79 | SMN1; SMN2 (0.58) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL23413007 | 0.79 | GAA (0.73) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29845687 | 0.79 | GAA (0.73) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11733765 | 0.78 | SMN1; SMN2 (0.64) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1935766 | 0.77 | GAA (0.70) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL2243374 | 0.76 | MAPT (0.72) | POLBGAASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015654-A | CONTAINING PYRAZOLOTRIAZOLE COUPLER IN ONE LIGHT-SENSITIVE SILVER HALIDE EMULSION LAYER AND DEVELOPER OXIDATION PRODUCT SCAVENGER IN SAME OR FURTHER LAYER | AGFA-GEVAERT NV (BE) | 2000-01-18 | — | — | US | disclosed |